Concerns have not been raised about the safety of antioxidants in food. However, high-dose supplements of antioxidants may be linked to health risks in some cases. Supplementing with high doses of beta-carotene may increase the risk of lung cancer in smokers. Supplementing with high doses of vitamin E may increase risks of prostate cancer and one type of stroke.http://www.chinavgchem.com/antioxidant/